RFC1 Antibody

The Replication factor C (RFC) heteropentamer includes RFC1, RFC2, RFC3, RFC4, and RFC5. The RFC heteropentamer is part of the multiprotein DNA replicase that functions to replicate DNA prior to cell division and repair DNA damage. RFC is the clamp loader ATPase associated with the DNA replicase. As the clamp loader, RFC uses ATP to recruit, open, and close the PCNA ring to link it to DNA for replication and repair. RFC1 is the 140 kDa subunit of RFC that has a DNA-binding domain with a BRCT motif and is suggested to play a more critical role than the other subunits.

Alternative names for RFC1 Antibody include replication factor C large subunit antibody, RF-C 140 kDa subunit antibody, activator 1 140 antibody, kDa subunit antibody, activator 1 large subunit antibody, A1 140 kDa subunit antibody, DNA-binding protein PO-GA antibody, RFC140 antibody, A1 antibody, PO-GA antibody, REC1 antibody, MHCBFB antibody, RFC140 antibody, MGC51786 antibody.