RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5’- 3’ RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex.
Alternative names for
RENT1 Antibody include regulator of nonsense transcripts 1 antibody, ATP-dependent helicase RENT1 antibody, nonsense mRNA reducing factor 1 antibody, NORF1 antibody, up-frameshift suppressor 1 homolog antibody, hUPF1 antibody, KIAA0221 antibody, FLJ43809 antibody, FLJ46894 antibody, KIAA0221 antibody.