REA Antibody

REA (repressor of estrogen receptor activity), also known as prohibitin 2, has been shown to exhibit a variety of functions that includes mitochondrial chaperone activity, cell cycle regulation, and transcriptional regulation. REA localizes to the mitochondria and associates with mitochondrial complex I where it may play a role in mitochondrial metabolism. REA interacts with pRb to inhibit E2F-mediated transcription as well as the estrogen receptor to repress estrogen-dependent transcription via recruitment of histone deacetylases.

Alternative names for REA Antibody include B-cell receptor-associated protein BAP37 antibody, D-prohibitin antibody, PHB2 antibody, BAP antibody, p22 antibody, BCAP37 antibody, PNAS-141 antibody, MGC117268 antibody.