RAP80 Antibody

RAP80 was first identified as a nuclear protein that interacts with the retinoid-related testis-associated receptor (RTR) and is able to inhibit the interaction of RTR with the N-CoR co-repressor. RAP80 has also been shown to interact with estrogen receptor alpha (ER-alpha) and modulate its activity. The modulation of ER-alpha activity is dependent on the ubiquitin-interacting motif (UIM) of RAP80. The UIM of RAP80 has also been demonstrated to be important for the BRCA1-dependent DNA repair response.

Alternative names for RAP80 Antibody include receptor-associated protein 80 antibody, ubiquitin interaction motif-containing protein 1 antibody, retinoid X receptor-interacting protein 110 antibody, nuclear zinc-finger protein RAP 80 antibody, UIMC1 antibody, RXRIP110 antibody, X2HRIP110 antibody.