Polycystin-2 Antibody

Polycystin-2 is a calcium permeable cation channel. Defects in the Polycystin-2 gene, PKD2, are the cause of polycystic kidney disease autosomal dominant type 2 (ADPKD2) which is characterized by progressive formation and enlargement of cysts in both kidneys, typically leading to end-stage renal disease in adult life. Cysts also occur in the liver and other organs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13563].

Alternative names for Polycystin-2 Antibody include PKD2 antibody, polycystic kidney disease 2 protein antibody, polysystwin antibody, transient receptor potential cation channel subfamily P member 2 antibody, R48321 antibody.