Polycystin-2 is a calcium permeable cation channel. Defects in the Polycystin-2 gene, PKD2, are the cause of polycystic kidney disease autosomal dominant type 2 (ADPKD2) which is characterized by progressive formation and enlargement of cysts in both kidneys, typically leading to end-stage renal disease in adult life. Cysts also occur in the liver and other organs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13563].
Alternative names for
Polycystin-2 Antibody include
Autosomal dominant polycystic kidney disease type II protein antibody,
Polycystic kidney disease 2 protein antibody,
polycystic kidney disease 2autosomal dominant) antibody,
autosomal dominant polycystic kidney disease type II protein antibody,
transient receptor potential cation channel, subfamily P, member 2 antibody.