DNA polymerase alpha is a four-subunit enzyme that exhibits DNA polymerase and primase activity. The four subunits of the heterotetrameric DNA pol alpha are A, B, C, and D. Subunit A displays the catalytic activity while the C and D subunits exhibit the primase activity. DNA polymerase (pol) alpha subunit B (PolA2) is the 70 kDa subunit that may serve to couple the DNA pol alpha-primase complex to the initiation/elongation machinery. DNA pol alpha is the only polymerase in eukaryotic cells that is capable of starting chains de novo.
Alternative names for
PolA2 Antibody include
DNA polymerase alpha subunit B antibody,
DNA polymerase alpha 70 kDa subunit antibody,
polymeraseDNA directed), alpha 2, accessory subunit antibody,
polymeraseDNA-directed), alpha70kD) antibody,
polymeraseDNA directed), alpha 270kD subunit) antibody.