DNA polymerase alpha is a four-subunit enzyme that exhibits DNA polymerase and primase activity. The four subunits of the heterotetrameric DNA pol alpha are A, B, C, and D. Subunit A displays the catalytic activity while the C and D subunits exhibit the primase activity. DNA polymerase (pol) alpha subunit B (PolA2) is the 70 kDa subunit that may serve to couple the DNA pol alpha-primase complex to the initiation/elongation machinery. DNA pol alpha is the only polymerase in eukaryotic cells that is capable of starting chains de novo.
Alternative names for
PolA2 Antibody include DNA polymerase alpha 70 kDa subunit antibody, DPOA2 antibody, POLA2 antibody.