Rad17 is a cell cycle checkpoint protein that associates with the RFC complex to recruit the 9-1-1 complex (Rad9, Hus1, Rad1) to sites of DNA damage. At DNA lesions, Rad17 and RFC aid in the activation of Chk2 by ATM and ATRIP to trigger the checkpoint signaling cascade for G2 arrest.
Alternative names for
Phospho Rad17 (S645) Antibody include
RAD1 homolog antibody,
Cell cycle checkpoint protein
RF-C/activator 1 homolog antibody,
RAD17 homologS. pombe) antibody,
cell cycle checkpoint protein
Rad17-like protein antibody,
RF-C activator 1 homolog antibody,
cell cycle checkpoint proteinRAD17) antibody.