EZH2 is a polycomb group enzyme that functions to methylate histone H3-lysine 27 and mediate gene silencing of Homeobox (Hox) genes during development. EZH2 possesses a SET domain which is important to methyltransferase activity. Amplification of EZH2 has been reported in a number of malignancies and may contribute to oncogenesis.
Alternative names for
Phospho EZH2 (S21) IHC Antibody include EZH2 antibody, Enhancer of Zeste Homolog 2 antibody, ENX-1 antibody, MGC9169 antibody.