PTPN12/PTP-PEST Antibody

PTPN12/PTP-PEST is a cytosolic protein tyrosine phosphatase (PTP) that contains a C-terminal PEST motif and plays an important role in cytoskeletal organization, immune cell activation, apoptosis, and embryonic development. PTPN12/PTP-PEST appears to contribute to these cellular processes through its interaction with a variety of signaling and cytoskeletal-associated proteins. The recent discovery that PTPN12/PTP-PEST is modulated by caspase-3 cleavage has led to the analysis of the role of PTPN12/PTP-PEST and other PTPs as regulators of apoptosis.

Alternative names for PTPN12/PTP-PEST Antibody include tyrosine-protein phosphatase non-receptor type 12 antibody, protein-tyrosine phosphatase G1 antibody, PTPG1 antibody.