PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling.
Alternative names for
PTEN Antibody include
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase
Mutated in multiple advanced cancers 1 antibody,
Phosphatase and tensin homolog antibody,
phosphatase and tensin homolog antibody,
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase
phosphatase and tensin-like protein antibody,
mutated in multiple advanced cancers 1 antibody,
MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody,
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody.