PTEN Antibody

PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling.

Alternative names for PTEN Antibody include mutated in multiple advanced cancers 1 antibody, MMAC1 antibody, TEP1 antibody, BZS antibody, MHAM antibody, MGC11227 antibody.