POLR3E Antibody

POLR3E (RNA polymerase III polypeptide E 80kDa) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3E is a specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. POLR3E plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9NVU0].

Alternative names for POLR3E Antibody include DNA-directed RNA polymerase III subunit RPC5 antibody, RNA polymerase III subunit C5 antibody, KIAA1452 antibody.