PIM1 is a member of the PIM family of proto-oncogenes that functions as a distinct class of serine/threonine protein kinases involved in growth factor signaling. PIM1 was originally identified as a target of proviral activation in T-cell lymphomas induced by Moloney murine leukemia virus. PIM1 appears to play a role in many aspects of cell growth, proliferation, and apoptosis. PIM1 is required for efficient cell cycle induction of peripheral T-cells in response to IL-2 signaling. PIM1 substrates include p21 cip1/waf1, CDC25A, PTP-U2, NuMA, and PAP-1.
Alternative names for
PIM1 Antibody include
pim-1 oncogene antibody,
Serine/threonine-protein kinase pim-1 antibody,
serine/threonine-protein kinase pim-1 antibody,
pim-1 kinase 44 kDa isoform antibody,
pim-1 oncogeneproviral integration site 1) antibody,
proto-oncogene serine/threonine-protein kinase pim-1 antibody.