PHD3 Antibody

PHD3 is one of 4 PHD (PHD1-4) enzymes that function as oxygen sensors and are responsible for the post-translational modification of HIF-1alpha, a component of a transcriptional complex involved in oxygen homeostasis. During normoxic levels, PHDs catalyze the hydroxylation of prolyl residues on HIF-1alpha and target it for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. The PHD isoforms appear to function in a non-redundant manner and may differ in their expression patterns and their catalytic selectivity.
    Product Specifications
    Catalog # Size Price
    PHD3 AntibodyReactivity: Human, Mouse
    Applications: WB
    Immunogen: Between 50 and 100
    A300-327A100 µl (1 mg/ml) $339Add to Cart
    A300-327A-M100 µl (10 blots) $229Add to Cart
    A300-327A-T20 µl (2 blots) $50Add to Cart

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