PDZ-GEF2 Antibody

PDZ-GEF2 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity. PDZ-GEF2 has been shown to activate Rap1A and Rap1B to promote the maturation of cell-cell adherens junctions.

Alternative names for PDZ-GEF2 Antibody include Rap guanine nucleotide exchange factor 6 antibody, PDZ domain-containing guanine nucleotide exchange factor 2 antibody, RAPGEF6 antibody, RA-GEF-2 antibody, RAGEF2 antibody, PDZGEF2 antibody, KIA001LB antibody.