PB1/BAF180 Antibody

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. PB1/BAF180 is a component of the SWI/SNF-B (PBAF) complex. It contains six bromodomains which are defined by a 110 amino-acid module that interacts with acetylated lysine and is found in many chromatin binding proteins and histone acetyltransferases. PB1/BAF180 has been proposed to function as a tumor suppressor protein. Recently, PB1/BAF180 has been found to play a role in mediating cell cycle arrest in response to DNA damage via the regulation of the tumor suppressor p21.
    Product Specifications
    Catalog # Size Price
    PB1/BAF180 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1 and 50
    A301-590A100 µl (1 mg/ml) $339Add to Cart
    A301-590A-T10 µl (1 mg/ml) $50Add to Cart
    PB1/BAF180 AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 1639 and 1689
    A301-591A100 µl (1 mg/ml) $339Add to Cart
    A301-591A-M100 µl (10 blots) $229Add to Cart
    A301-591A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A301-590A and A301-591A
    A310-563A1 Pack $472Add to Cart

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