PARN Antibody

Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. PARN prefers poly(A) as the substrate, hence, it efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. PARN is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons [taken from NCBI Entrez Gene (Gene ID: 5073)].
    Product Specifications
    Catalog # Size Price
    PARN AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 539 and 589
    A303-561A100 µl (1 mg/ml) $339Add to Cart
    A303-561A-M100 µl (10 blots) $229Add to Cart
    A303-561A-T20 µl (2 blots) $50Add to Cart
    PARN AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 589 and 639
    A303-562A100 µl (1 mg/ml) $339Add to Cart
    A303-562A-M100 µl (10 blots) $229Add to Cart
    A303-562A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A303-561A and A303-562A
    A311-310A1 Pack $472Add to Cart

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