PARN Antibody

Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. PARN prefers poly(A) as the substrate, hence, it efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. PARN is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons [taken from NCBI Entrez Gene (Gene ID: 5073)].
    Product/Catalog #SpecificationsPrice
    PARN Antibody
    A303-561A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    PARN Antibody
    A303-562A
    Reactivity: Human
    Applications: WB, IP
    $314.00
    Bulk Quote
    Data Sheet
    Add to Cart
    PARN Antibody AbVantage™ Pack
    A311-310A
    Applications: WB, IP
    Reactivity: Human
    Quantity: 1 each of A303-561A and A303-562A
    $437.00
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    Data Sheet
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