Notch1 Antibody

Notch1 is the human homolog of the D. melanogaster Notch gene first reported as the gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch protein is a transmembrane receptor that mediates juxtacrine signals between adjacent cells. Mammalian Notch1 ligands include Delta-like and Jagged. Upon ligand binding, Notch1 undergoes two proteolytic cleavage events that result in the release of the intracellular Notch1 domain and its translocation to the nucleus where it can participate in gene transactivation. Notch 1 signals mediate cellular fate, differentiation, and development.
    Product/Catalog #SpecificationsPrice
    Notch1 Antibody
    A301-894A
    Reactivity: Human
    Applications: IP, PLA
    $314.00
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    Notch1 Antibody
    A301-895A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    Notch1 Antibody AbVantage™ Pack
    A310-672A
    Applications: WB, IP, PLA
    Reactivity: Human
    Quantity: 1 each of A301-894A and A301-895A
    $437.00
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    Notch1 IHC Antibody
    IHC-00538
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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