Notch1 Antibody

Notch1 is the human homolog of the D. melanogaster Notch gene first reported as the gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch protein is a transmembrane receptor that mediates juxtacrine signals between adjacent cells. Mammalian Notch1 ligands include Delta-like and Jagged. Upon ligand binding, Notch1 undergoes two proteolytic cleavage events that result in the release of the intracellular Notch1 domain and its translocation to the nucleus where it can participate in gene transactivation. Notch 1 signals mediate cellular fate, differentiation, and development.
    Product Specifications
    Catalog # Size Price
    Notch1 AntibodyReactivity: Human
    Applications: IP, PLA
    Immunogen: Between 2400 and 2450
    A301-894A100 µl (1 mg/ml) $339Add to Cart
    A301-894A-T10 µl (1 mg/ml) $50Add to Cart
    Notch1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 2505 and 2555
    A301-895A100 µl (1 mg/ml) $339Add to Cart
    A301-895A-M100 µl (10 blots) $229Add to Cart
    A301-895A-T20 µl (2 blots) $50Add to Cart
    Notch1 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 2505 and 2555
    IHC-00538100 µl (50 slides) $360Add to Cart
    Applications: WB, IP, IHC-P, IF, PLA
    Reactivity: Human
    Includes: 1 each of A301-894A and A301-895A
    A310-672A1 Pack $472Add to Cart

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