The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. About 30 different human Nups have been identified and appear to serve non-redundant functions. Nup210 is a membrane-spanning glycoprotein and major component of the NPC. It is essential for nuclear envelope structure and cell viability. Autoantibodies to Nup210 have been observed in patients with primary biliary cirrhosis (PBC), an autoimmune liver disease.
Alternative names for
NUP210 Antibody include POM210 antibody,
Nuclear pore membrane glycoprotein 210 antibody,
Nuclear envelope pore membrane protein POM 210 antibody,
Pore membrane protein of 210 kDa antibody,
nucleoporin 210kDa antibody,
nuclear pore membrane glycoprotein 210 antibody,
nuclear pore protein gp210 antibody,
pore membrane protein of 210 kDa antibody,
nuclear envelope pore membrane protein POM 210 antibody.