NUMB Antibody

NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.
    Product Specifications
    Catalog # Size Price
    NUMB AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 375 and 425
    A301-714A100 µl (0.2 mg/ml) $339Add to Cart
    A301-714A-M100 µl (10 blots) $229Add to Cart
    A301-714A-T20 µl (2 blots) $50Add to Cart
    NUMB AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 525 and 575
    A301-715A100 µl (1 mg/ml) $339Add to Cart
    A301-715A-T10 µl (1 mg/ml) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A301-714A and A301-715A
    A310-609A1 Pack $472Add to Cart

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