NUMA Antibody

The nuclear mitotic apparatus protein (NuMA) is a critical component of the mitotic spindle that is responsible for organizing minus-ends of microtubules at spindle poles. NUMA is regulated by phosphorylation and associates with dynein and dynactin in its phosphorylated form. Dephosphorylation of NUMA in anaphase results in the release from dynein and dynactin to allow spindle disassembly. NUMA, in association with dynein and dynactin, also interacts with 4.1R in a complex of spindle pole organizing proteins. Other NUMA interacting proteins include GAS41, tankyrase, and Rae1. These interactions indicate a broader role for NUMA function in the nucleus.
    Product Specifications
    Catalog # Size Price
    NUMA AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 900 and 950
    A301-509A100 µl (0.2 mg/ml) $339Add to Cart
    A301-509A-M100 µl (10 blots) $229Add to Cart
    A301-509A-T20 µl (2 blots) $50Add to Cart
    NUMA AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 2065 and 2115
    A301-510A100 µl (0.2 mg/ml) $339Add to Cart
    A301-510A-M100 µl (10 blots) $229Add to Cart
    A301-510A-T20 µl (2 blots) $50Add to Cart
    NUMA IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 900 and 950
    IHC-00302100 µl (50 slides) $360Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A301-509A and A301-510A
    A310-529A1 Pack $472Add to Cart

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