NUMA Antibody

The nuclear mitotic apparatus protein (NuMA) is a critical component of the mitotic spindle that is responsible for organizing minus-ends of microtubules at spindle poles. NUMA is regulated by phosphorylation and associates with dynein and dynactin in its phosphorylated form. Dephosphorylation of NUMA in anaphase results in the release from dynein and dynactin to allow spindle disassembly. NUMA, in association with dynein and dynactin, also interacts with 4.1R in a complex of spindle pole organizing proteins. Other NUMA interacting proteins include GAS41, tankyrase, and Rae1. These interactions indicate a broader role for NUMA function in the nucleus.
    Product/Catalog #SpecificationsPrice
    NUMA Antibody
    A301-509A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    NUMA Antibody
    A301-510A
    Reactivity: Human
    Applications: WB, IP, IHC-P, IF
    $314.00
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    NUMA Antibody AbVantage™ Pack
    A310-529A
    Applications: WB, IP
    Reactivity: Human
    Quantity: 1 each of A301-509A and A301-510A
    $437.00
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    NUMA IHC Antibody
    IHC-00302
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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