NIPBL Antibody

The NIPBL (Nipped B-like) gene was originally identified as a gene mutated in individuals with Cornelia de Lange syndrome (CdLS), a heterogenous developmental disorder associated with multiple anatomical malformations. The NIPBL protein product is also referred to as delangin. It has substantial homology to the D. melanogaster Nipped-B protein which is related to a family of chromosomal adherins that plays a role in sister chromatid adhesion, chromosome condensation, and DNA repair. A study of metaphase spreads from individuals positive and negative for NIPBL mutations revealed an association between NIPBL mutations and precocious sister chromatid separation. This result suggests a function for NIPBL that is similar to its homolog in drosophila.
    Product Specifications
    Catalog # Size Price
    NIPBL AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 550 and 600
    A301-778A100 µl (1 mg/ml) $339Add to Cart
    A301-778A-T10 µl (1 mg/ml) $50Add to Cart
    NIPBL AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1025 and 1075
    A301-779A100 µl (1 mg/ml) $339Add to Cart
    A301-779A-M100 µl (10 blots) $229Add to Cart
    A301-779A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A301-778A and A301-779A
    A310-635A1 Pack $472Add to Cart

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