NHERF1 Antibody

NHERF1 (sodium-hydrogen exchanger regulatory factor 1) is a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer [taken from NCBI Entrez Gene (Gene ID: 9368)].

Alternative names for NHERF1 Antibody include Solute carrier family 9 isoform A3 regulatory factor 1 antibody, SLC9A3R1 antibody, Ezrin-radixin-moesin-binding phosphoproten 50 antibody, EBP50 antibody, NHERF antibody.