NFAT3 (nuclear factor of activated T-cells 3) plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. NFAT3 is transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. NFAT3 increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. It may also play an important role in myotube differentiation, cardiac development and hypertrophy, and in deafferentation-induced apoptosis of sensory neurons [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14934].
Alternative names for
NFAT3 Antibody include nuclear factor of activated T-cells 3 cytplasmic 4 antibody, NF-ATc4 antibody, NFATc4 antibody, T-cell transcription factor NFAT3 antibody, NF-AT3 antibody.