The NFKB2 gene encodes a 100 kDa protein that can undergo co-translational processing to also yield a 52 kDa protein. The 52 kDa protein is also known as NF-kappa B2/p52 and is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The 100 kDa product is also known as p100 or I kappa B delta. P100/I kappa B delta has been shown to function as an inhibitor protein that interacts with NF-kappa B and inhibit its DNA binding activity. P100/I kappa B delta is a member of the I kappa B family of proteins which includes I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa B1/p105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. The classical description of the NF-kappa B transcription factor is a transcription factor that reprograms gene expression of the immune system in response to injury, infection, and stress.
Alternative names for
NF-kappaB2 Antibody include H2TF1 antibody,
Oncogene Lyt-10 antibody,
oncogene Lyt-10 antibody,
Nuclear factor NF-kappa-B p100 subunit antibody,
DNA-binding factor KBF2 antibody,
Lymphocyte translocation chromosome 10 protein antibody,
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 antibody,
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2p49/p100) antibody,
nuclear factor NF-kappa-B p100 subunit antibody,
lymphocyte translocation chromosome 10 protein antibody,
nuclear factor of kappa light chain gene enhancer in B-cells 2 antibody.