NEDD4L Antibody

NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5 [taken from the Universal Protein Resource (UniProt) wwwuniprotorg/uniprot/Q96PU5]
    Product Specifications
    Catalog # Size Price
    NEDD4L AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 225 and 275
    A302-512A100 µl (0.2 mg/ml) $339Add to Cart
    A302-512A-M100 µl (10 blots) $229Add to Cart
    A302-512A-T20 µl (2 blots) $50Add to Cart
    NEDD4L AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 275 and 325
    A302-513A100 µl (0.2 mg/ml) $339Add to Cart
    A302-513A-M100 µl (10 blots) $229Add to Cart
    A302-513A-T20 µl (2 blots) $50Add to Cart
    NEDD4L AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 425 and 475
    A302-514A100 µl (0.2 mg/ml) $339Add to Cart
    A302-514A-M100 µl (10 blots) $229Add to Cart
    A302-514A-T20 µl (2 blots) $50Add to Cart
    NEDD4L IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 275 and 325
    IHC-00713100 µl (50 slides) $360Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human, Mouse
    Includes: 1 each of A302-512A, A302-513A and A302-514A
    A310-914A1 Pack $707Add to Cart

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