NEDD4L Antibody

NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5 [taken from the Universal Protein Resource (UniProt) wwwuniprotorg/uniprot/Q96PU5]
    Product/Catalog #SpecificationsPrice
    NEDD4L Antibody
    A302-512A
    Reactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    $314.00
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    NEDD4L Antibody
    A302-513A
    Reactivity: Human, Mouse
    Applications: WB, IP, IHC-P, IF
    $314.00
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    Data Sheet
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    NEDD4L Antibody
    A302-514A
    Reactivity: Human, Mouse
    Applications: WB, IP
    $314.00
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    NEDD4L Antibody AbVantage™ Pack
    A310-914A
    Applications: WB, IP
    Reactivity: Human, Mouse
    Quantity: 1 each of A302-512A, A302-513A and A302-514A
    $655.00
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    NEDD4L IHC Antibody
    IHC-00713
    Applications: IHC-P, IF
    Reactivity: Human, Mouse
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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