Myo18A/Myosin XVIIIA Antibody

Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.

Alternative names for Myo18A/Myosin XVIIIA Antibody include myosin containing a PDZ domain antibody, molecule associated with JAK3 N-terminus antibody, MAJN antibody, KIAA0216 antibody, MYSPDZ antibody, SPR210 antibody.