Menin Antibody

Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes.
    Product Specifications
    Catalog # Size Price
    Menin AntibodyReactivity: Human, Mouse
    Applications: WB, IP, IHC-P, ICC, IF, ChIP-PCR
    Immunogen: Between 575 and C-term
    A300-105A100 µl (1 mg/ml) $339Add to Cart
    A300-105A-M100 µl (10 blots) $229Add to Cart
    A300-105A-T20 µl (2 blots) $50Add to Cart
    Menin AntibodyReactivity: Human, Mouse
    Applications: WB, IP, PLA
    Immunogen: Between 575 and C-term
    A300-106A100 µl (1 mg/ml) $339Add to Cart
    A300-106A-M100 µl (10 blots) $229Add to Cart
    A300-106A-T20 µl (2 blots) $50Add to Cart
    Menin AntibodyReactivity: Human, Mouse
    Applications: WB, IP
    Immunogen: Between 575 and C-term
    A300-106B100 µg $362Add to Cart
    Menin AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 500 and 550
    A300-115A100 µl (1 mg/ml) $339Add to Cart
    A300-115A-T10 µl (1 mg/ml) $50Add to Cart
    Reactivity: Human, Mouse
    Applications: IP
    Immunogen: Between 575 and C-term
    S300-105100 µg $356Add to Cart
    Menin Monoclonal AntibodyApplications: WB, IP, IHC-P
    Reactivity: Human
    Immunogen: Between 575 and C-term
    A500-003A0.1 ml (20 - 100 blots) $339Add to Cart
    Menin IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human, Mouse
    Immunogen: Between 575 and C-term
    IHC-00572100 µl (50+ slides) $360Add to Cart
    IHC-00572-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, ICC, IF, ChIP-PCR, PLA
    Reactivity: Human, Mouse
    Includes: 1 each of A300-105A, A300-106A and A300-115A
    A310-027A1 Pack $707Add to Cart

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