Mel-18 Antibody

Mel18 is a transcriptional repressor and binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel-18 is a component of a polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Mel-18 has tumor suppressor activity. Mel-18 plays a role in control of cell proliferation and/or neural cell development, and also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. [taken from the Universal Protein Resource (UniProt) P35227].
    Product Specifications
    Catalog # Size Price
    Mel-18 AntibodyReactivity: Human
    Applications: WB
    Immunogen: Between 125 and 175
    A303-580A100 µl (1 mg/ml) $339Add to Cart
    A303-580A-M100 µl (10 blots) $229Add to Cart
    A303-580A-T20 µl (2 blots) $50Add to Cart

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