MTA3 Antibody

MTA3 (metastasis-associated protein 3) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA3 is a member of a family of proteins (MTA1-3) differentially expressed in metastatic breast cancer cells. MTA3 functions as a repressor of the transcription factor Snail, a factor involved in epithelial to mesenchymal transitions. MTA3 expression is estrogen dependent in breast cancer cells. Studies show that ERalpha selectively bind the MTA3 promoter in an SP1-dependent fashion to stimulate MTA3 gene transcription.
    Product Specifications
    Catalog # Size Price
    MTA3 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 400 and 450
    A300-160A100 µl (1 mg/ml) $339Add to Cart
    MTA3 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 400 and 450
    IHC-00423100 µl (50 slides) $360Add to Cart

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