MGRN1 Antibody

MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O60291].
    Product/Catalog #SpecificationsPrice
    MGRN1 Antibody
    A302-912A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    MGRN1 Antibody
    A302-913A
    Reactivity: Human
    100% Sequence Identity:
    Applications: IP
    $314.00
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    Data Sheet
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    MGRN1 Antibody AbVantage™ Pack
    A311-076A
    Applications: WB, IP
    Reactivity: Human
    Quantity: 1 each of A302-912A and A302-913A
    $437.00
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    Data Sheet
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