MGRN1 Antibody

MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) O60291].
    Product Specifications
    Catalog # Size Price
    MGRN1 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 400 and 450
    A302-912A100 µl (0.2 mg/ml) $339Add to Cart
    A302-912A-M100 µl (10 blots) $229Add to Cart
    A302-912A-T20 µl (2 blots) $50Add to Cart
    MGRN1 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 505 and 555
    A302-913A100 µl (1 mg/ml) $339Add to Cart
    A302-913A-T10 µl (1 mg/ml) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A302-912A and A302-913A
    A311-076A1 Pack $472Add to Cart

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