MERIT40 Antibody

MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NWV8]
    Product Specifications
    Catalog # Size Price
    MERIT40 AntibodyReactivity: Human
    Applications: IP
    Immunogen: Between 1 and 50
    A302-515A100 µl (1 mg/ml) $339Add to Cart
    A302-515A-T10 µl (1 mg/ml) $50Add to Cart
    MERIT40 AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 175 and 225
    A302-516A100 µl (1 mg/ml) $339Add to Cart
    A302-516A-T10 µl (1 mg/ml) $50Add to Cart

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