MED18 is a component of the multisubunit mediator complex that functions as a bridge between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. MED18 forms a subcomplex with the MED8 and MED20 subunits and plays an important role in initiation complex formation.
Alternative names for
MED18 Antibody include mediator of RNA polymerase II transcription subunit 18 antibody, mediator complex subunit 18 antibody, p28b antibody, FLJ20045 antibody.