MED15 Antibody

Mediator complex subunit 15 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. MED15 is required for cholesterol-dependent gene regulation. It also positively regulates the Nodal signaling pathway. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96RN5].

Alternative names for MED15 Antibody include positive cofactor 2 glutamine/Q-rich-associated protein antibody, PC2 glutamine/Q-rich-associated protein antibody, TPA-inducible gene 1 protein antibody, TIG-1 antibody, activator-recruited cofactor 105 kDa component antibody, ARC105 antibody, CTG repeat protein 7a antibody, trinucleotide repeat-containing gene 7 protein antibody, CAG7A antibody, TIG1 antibody, CTG7A antibody, PCQAP antibody, TNRC7 antibody.