MED13L Antibody

Mediator complex subunit 13-like is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q71F56].

Alternative names for MED13L Antibody include thyroid hormone receptor-associated protein 2 antibody, thyroid hormone receptor-associated protein complex 240 kDa component-like antibody, THRAP2 antibody, TRAP240L antibody, PROSIT240 antibody, KIAA1025 antibody.