MDC1 Antibody

MDC1 is required for the S- and G2/M-checkpoint-mediated cell cycle arrest in response to DNA damage. MDC1 interacts with H2AX near sites of DNA double-strand breaks and recruits ATM kinase to foci of DNA damage. MDC1 also appears to regulate the function of other proteins involved in the DNA damage checkpoint such as BRCA1 and Chk2.

Alternative names for MDC1 Antibody include mediator of DNA damage checkpoint protein 1 antibody, nuclear factor with BRCT domains 1 antibody, KIAA0170 antibody, NFBD1 antibody, DKFZp781A0122 antibody.