The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM8 and cdc6 are required for origin-binding of the MCM2-7 complex. MCM8 functions in the activation of the pre-recognition complex during G1 by recruiting cdc6 to the origins of DNA replication.
Alternative names for
MCM8 Antibody include
REC homolog antibody,
Minichromosome maintenance 8 antibody,
minichromosome maintenance complex component 8 antibody,
DNA replication licensing factor
MCM8 minichromosome maintenance deficient 8 antibody.