MCM-BP Antibody

MCM-binding protein is an associated component of the MCM (mini-chromosome maintenance) complex that acts as a regulator of DNA replication. MCM-BP binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. MCM-BP is required for sister chromatid cohesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BTE3].
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