MCAK Antibody

Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.
    Product Specifications
    Catalog # Size Price
    MCAK AntibodyReactivity: Human
    Applications: IP, IHC-P, IF
    Immunogen: Between 50 and 100
    A300-806A100 µl (1 mg/ml) $339Add to Cart
    A300-806A-T10 µl (1 mg/ml) $50Add to Cart
    MCAK AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 550 and 600
    A300-807A100 µl (1 mg/ml) $339Add to Cart
    A300-807A-M100 µl (10 blots) $229Add to Cart
    A300-807A-T20 µl (2 blots) $50Add to Cart
    MCAK AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 675 and C-term
    A300-808A100 µl (0.2 mg/ml) $339Add to Cart
    A300-808A-M100 µl (10 blots) $229Add to Cart
    A300-808A-T20 µl (2 blots) $50Add to Cart
    MCAK AntibodyReactivity: Mouse
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 50 and 100
    A300-921A100 µl (1 mg/ml) $339Add to Cart
    A300-921A-M100 µl (10 blots) $229Add to Cart
    A300-921A-T20 µl (2 blots) $50Add to Cart
    MCAK AntibodyReactivity: Mouse
    Applications: IP
    Immunogen: Between 550 and 600
    A300-922A100 µl (1 mg/ml) $339Add to Cart
    A300-922A-T10 µl (1 mg/ml) $50Add to Cart
    MCAK IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 50 and 100
    IHC-00501100 µl (50+ slides) $360Add to Cart
    IHC-00501-T10 µl (5+ slides) $50Add to Cart
    MCAK IHC AntibodyApplications: IHC-P, IF
    Reactivity: Mouse
    Immunogen: Between 50 and 100
    IHC-00502100 µl (50+ slides) $360Add to Cart
    IHC-00502-T10 µl (5+ slides) $50Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Includes: 1 each of A300-806A, A300-807A and A300-808A
    A310-252A1 Pack $707Add to Cart
    Applications: WB, IP, IHC-P, IF
    Reactivity: Mouse
    Includes: 1 each of A300-921A and A300-922A
    A310-294A1 Pack $472Add to Cart

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