MCAK Antibody

Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division.
    Product/Catalog #SpecificationsPrice
    MCAK Antibody
    A300-806A
    Reactivity: Human
    Applications: IP, IHC-P, IF
    $314.00
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    MCAK Antibody
    A300-807A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    MCAK Antibody
    A300-808A
    Reactivity: Human
    Applications: WB, IP
    $314.00
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    MCAK Antibody
    A300-921A
    Reactivity: Mouse
    100% Sequence Identity:
    Applications: WB, IP, IHC-P, IF
    $314.00
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    MCAK Antibody
    A300-922A
    Reactivity: Mouse
    100% Sequence Identity:
    Applications: IP
    $314.00
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    MCAK Antibody AbVantage™ Pack
    A310-252A
    Applications: WB, IP, IHC-P, IF
    Reactivity: Human
    Quantity: 1 each of A300-806A, A300-807A and A300-808A
    $655.00
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    MCAK Antibody AbVantage™ Pack
    A310-294A
    Applications: WB, IP, IHC-P, IF
    Reactivity: Mouse
    Quantity: 1 each of A300-921A and A300-922A
    $437.00
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    MCAK IHC Antibody
    IHC-00501
    Applications: IHC-P, IF
    Reactivity: Human
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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    MCAK IHC Antibody
    IHC-00502
    Applications: IHC-P, IF
    Reactivity: Mouse
    100% Sequence Identity:
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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