MBD2 Antibody

MBD2 (methyl-CpG-binding domain protein 2) binds methylated CpG sites and represses gene transcription. DNA methylation is a common mechanism of gene silencing and is central to the developmental process. Methyl-CpG binding proteins (MBPs) have a high affinity for methylated DNA and are proposed to mediate gene silencing via the recruitment of histone deacetylases and other transcriptional repressors to chromatin.

Alternative names for MBD2 Antibody include MBD2 antibody, MBD-2 antibody, methyl-CpG binding domain protein 2 antibody, DMTase antibody, demethylase antibody.