MAP126/Astrin Antibody

Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta).
    Product/Catalog #SpecificationsPrice
    Astrin/MAP126 Antibody
    A301-511A
    Reactivity: Human
    Applications: IP
    $314.00
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    Astrin/MAP126 Antibody
    A301-512A
    Reactivity: Human
    100% Sequence Identity:
    Applications: WB, IP
    $314.00
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    Astrin/MAP126 Antibody AbVantage™ Pack
    A310-530A
    Applications: WB, IP
    Reactivity: Human
    Quantity: 1 each of A301-511A and A301-512A
    $437.00
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    Data Sheet
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