LYN Antibody

LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. It is involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. LYN induces SAPK by a MKK7- and MEKK1-dependent mechanism [taken from the Universal Protein Resource (UniProt)].
    Product Specifications
    Catalog # Size Price
    LYN AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1 and 50
    A302-683A100 µl (1 mg/ml) $339Add to Cart
    A302-683A-M100 µl (10 blots) $229Add to Cart
    A302-683A-T20 µl (2 blots) $50Add to Cart

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