LATS2 (Large Tumor Suppressor homolog 2) has been identified as a tumor suppressor protein and is a member of the Dbf2-related (NDR) family of protein kinases that are key components of the mitotic exit network. LATS2 appears to negatively regulate G2/M transitioning by down-regulating CDC2 kinase activity. LATS2 has also been identified as a negative regulator of the androgen receptor (AR) and may play a role in AR-mediated transcription and the development of prostate cancer.
Alternative names for
LATS2 Antibody include
Kinase phosphorylated during mitosis protein antibody,
Large tumor suppressor homolog 2 antibody,
Serine/threonine-protein kinase kpm antibody,
Warts-like kinase antibody,
large tumor suppressor kinase 2 antibody,
warts-like kinase antibody,
serine/threonine kinase KPM antibody,
large tumor suppressor homolog 2 antibody,
serine/threonine-protein kinase kpm antibody,
LATS, large tumor suppressor, homolog 2 antibody,
kinase phosphorylated during mitosis protein antibody,
LATSlarge tumor suppressor, Drosophila) homolog 2 antibody.