Kaiso Antibody

Transcriptional regulator Kaiso possesses bimodal DNA-binding specificity and binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Kaiso contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. [taken from NCBI Entrez Gene (Gene ID: 10009)].
    Product Specifications
    Catalog # Size Price
    Kaiso AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 375 and 425
    A303-557A100 µl (1 mg/ml) $339Add to Cart
    A303-557A-M100 µl (10 blots) $229Add to Cart
    A303-557A-T20 µl (2 blots) $50Add to Cart
    Kaiso AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 622 and 672
    A303-558A100 µl (1 mg/ml) $339Add to Cart
    A303-558A-M100 µl (10 blots) $229Add to Cart
    A303-558A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A303-557A and A303-558A
    A311-309A1 Pack $472Add to Cart

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