The gene that encodes KANK1 (KN motif and ANKyrin repeat-domain-containing protein 1) was originally identified in a chromosomal region that exhibited loss of heterozygosity in renal cell carcinoma. KANK1 bears five ankyrin repeats and a conserved motif at the N-terminus which contains motifs for nuclear localization and export signals (KN-motif). It functions to regulate actin stress fiber formation and has been found to be a substrate of Akt and to bind 14-3-3.
Alternative names for
KANK1 Antibody include kidney ankyrin repeat-containing protein antibody, ankyrin repeat domain-containing protein 15 antibody, KANK antibody, ANKRD15 antibody, KIAA0172 antibody.