JMJD1B is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD1B was identified as the 5qNCA gene that lies within a locus on chromosome 5 that is frequently deleted in myeloid leukemias and myelodysplasias. JMJD1B has been demonstrated to have growth suppressive activity and is implicated as a tumor suppressor gene.
Alternative names for
JMJD1B Antibody include KDM3B antibody,
Lysine-specific demethylase 3B antibody,
JmjC domain-containing histone demethylation protein 2B antibody,
Jumonji domain-containing protein 1B antibody,
Nuclear protein 5qNCA antibody,
lysineK)-specific demethylase 3B antibody,
lysine-specific demethylase 3B antibody,
nuclear protein 5qNCA antibody,
jumonji domain containing 1B antibody,
jumonji domain-containing protein 1B antibody,
jmjC domain-containing histone demethylation protein 2B antibody.