JARIDB IHC Antibody

JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer.

Alternative names for JARIDB IHC Antibody include Jarid1B antibody, Jumonji antibody, AT rich interactive domain 1B antibody , PLU1 antibody, PLU-1 antibody, putative DNA/chromatin binding motif antibody, RBP2-like retinoblastoma-binding protein 2 homolog 1A antibody, RBP2-H1 antibody, cancer/testis antigen 31 antibody, CT31 antibody, PUT1 antibody, KDM5B antibody.