Gemin5 Antibody

Gemin5 is a component of the SMN (survival of motor neurons) complex. The SMN complex is composed of the SMN protein and several Gemins (2-7) and is involved in the assembly of snRNPs in the cytoplasm and their transport to the nucleus. The SMN complex localizes to nuclear focal structures called gems or Gemini of coiled bodies. Gemin 5 has been shown to be responsible for recognizing and binding the snRNP code during snRNP biogenesis. Recent studies have shown that Gemin 5 is rarely detectable in SMN complexes associated with gems/Cajal bodies in the nucleus and may play a specific role in cytoplasmic SMN complexes. It has also been shown to function as a scaffold protein for ASK1-JNK1 signaling.
    Product Specifications
    Catalog # Size Price
    Gemin5 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1360 and 1410
    A301-325A100 µl (0.2 mg/ml) $339Add to Cart
    A301-325A-M100 µl (10 blots) $229Add to Cart
    A301-325A-T20 µl (2 blots) $50Add to Cart
    Gemin5 AntibodyReactivity: Human
    Applications: WB, IP
    Immunogen: Between 1410 and 1438
    A301-326A100 µl (0.2 mg/ml) $339Add to Cart
    A301-326A-M100 µl (10 blots) $229Add to Cart
    A301-326A-T20 µl (2 blots) $50Add to Cart
    Applications: WB, IP
    Reactivity: Human
    Includes: 1 each of A301-325A and A301-326A
    A310-454A1 Pack $472Add to Cart

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