GTF3C2/TFIIIC110 Antibody

General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.

Alternative names for GTF3C2/TFIIIC110 Antibody include transcription factor IIIC subunit beta antibody, TF3C-beta antibody, TFIIIC 110 kDa subunit antibody, general transcription factor IIIC polypeptide 2 (beta subunit antibody, 110 kDa) antibody, KIAA0011 antibody.