P66beta/GATAD2B interacts with MBD2 (methyl-CpG-binding domain 2) and MBD3 (methyl-CpG-binding domain 3) and participates in transcriptional repression in association with the MBD2/NuRD and MBD3/NuRD histone deacetylase complexes. P66beta/GATAD2B is SUMOylated in vivo and its repressive activity has been shown to be enhanced by SUMOylation.
Alternative names for
GATAD2B.p66beta IHC Antibody include p66/p68 antibody,
Transcriptional repressor p66-beta antibody,
GATA zinc finger domain-containing protein 2B antibody,
GATA zinc finger domain containing 2B antibody,
transcriptional repressor p66-beta antibody,
transcription repressor p66 beta component of the MeCP1 complex antibody.