Flightless-1 Antibody

Flightless-1 is the human homolog of the drosophila flightless (fli1), a gene required for proper development of flight muscles and essential to embryonic development. It is a member of the gelsolin family of actin-binding proteins, and is highly conserved among vertebrates and invertebrates. The actin-remodeling activity of flightless-1 may have multiple roles in the cell. Studies in transgenic mice indicate a role in wound healing that may involve the regulation of cell migration and proliferation. Flightless-1 has also been found to be associated with complexes involved in transcriptional regulation. It associates with CARM1, a protein arginine methyltransferase, and may function as a nuclear receptor coactivator via this interaction. It has also been shown to associate with the BAF53a subunit of the SWI/SNF-like chromatin remodeling complexes.
    Product Specifications
    Catalog # Size Price
    Flightless-1 AntibodyReactivity: Human
    Applications: WB, IP, IHC-P, IF
    Immunogen: Between 425 and 475
    A301-565A100 µl (0.2 mg/ml) $339Add to Cart
    A301-565A-M100 µl (10 blots) $229Add to Cart
    A301-565A-T20 µl (2 blots) $50Add to Cart
    Flightless-1 IHC AntibodyApplications: IHC-P, IF
    Reactivity: Human
    Immunogen: Between 425 and 475
    IHC-00340100 µl (50+ slides) $360Add to Cart
    IHC-00340-T10 µl (5+ slides) $50Add to Cart

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