Flightless-1 Antibody

Flightless-1 is the human homolog of the drosophila flightless (fli1), a gene required for proper development of flight muscles and essential to embryonic development. It is a member of the gelsolin family of actin-binding proteins, and is highly conserved among vertebrates and invertebrates. The actin-remodeling activity of flightless-1 may have multiple roles in the cell. Studies in transgenic mice indicate a role in wound healing that may involve the regulation of cell migration and proliferation. Flightless-1 has also been found to be associated with complexes involved in transcriptional regulation. It associates with CARM1, a protein arginine methyltransferase, and may function as a nuclear receptor coactivator via this interaction. It has also been shown to associate with the BAF53a subunit of the SWI/SNF-like chromatin remodeling complexes.
    Product/Catalog #SpecificationsPrice
    Flightless-1 Antibody
    A301-565A
    Reactivity: Human
    100% Sequence Identity:
    Applications: WB, IP, IHC-P, IF
    $314.00
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    Data Sheet
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    Flightless-1 IHC Antibody
    IHC-00340
    Applications: IHC-P, IF
    Reactivity: Human
    100% Sequence Identity:
    Quantity: 0.1 ml (50 - 250 slides)
    $360.00
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    Data Sheet
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